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Magnesium

Magnesium is an element predominantly found in bone, approximately 65%, with 35% in cells.

It is vital for energy production, muscle contraction, nerve function, and the maintenance of strong bones. Magnesium levels tend to follow that of K+ and Ca+.

Gastrointestinal absorption and normal renal excretion regulate serum magnesium levels. Abnormal magnesium levels can result in various metabolic abnormalities and clinical manifestations.

Clinical Details

Risk factors for low magnesium include:

  • Inadequate dietary intake (elderly, malnutrition, alcoholism)
  • Poor absorption in gastrointestinal disorders (IBD)
  • Excessive loss – severe prolonged diarrhoea, prolonged use of loop diuretics
  • Ketoacidosis
  • Accompanying hypocalcaemia or hypokalaemia
  • Patients receiving TPN
  • Severe burns
  • Toxaemia of pregnancy

Complications of low magnesium include unexplained hypocalcaemia, refractory hypokalaemia, cardiac arrhythmias, tetany or seizures.

Risk factors for high magnesium include:

  • Hypermagnesaemia is predominantly the result of renal failure
  • Iatrogenic causes from excessive supplementation or over use of laxatives
  • Dehydration
  • Hyperparathyroidism
  • Hypothyroidism
  • DKA – initial presentation

Complications of high magnesium can manifest with levels above 2mmol/l. Severely increased levels can result in muscle weakness progressing to a flaccid paralysis, confusion, respiratory paralysis, complete heart block and cardiac arrest in extreme cases.

 

 

Case Study
At Enfer Medical, we have integrated a cutting-edge and fully automated WASPLab® (Walk Away Specimen Processor) that has significantly enhanced our testing capabilities to ensure the highest of quality when processing patient samples.
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WASPLab® at Enfer Medical
Our entire microbiology workflow has been optimized using automation and highly sophisticated robots to ensure uninterrupted incubation for rapid bacterial growth and improved turnaround times for patients.
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Our Services

Service
Health & Wellness
General health and wellness testing can include a variety of tests, depending on the needs of the individual or recommendations of
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Sexual Health
Regular STI screening facilitates early treatment and reduces the long-term consequences of infection.
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Respiratory Health
Rapid early pathogen identification has important treatment and infection control implications. See our range of tests here.
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Reproductive & Female Health
Hormonal analysis is hugely beneficial to identifying problems that can arise during the reproductive years.
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Sample Type &
Volume Required

5mL venous serum or plasma

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Transporting
Samples

In addition to the packaging of samples, the transport/delivery of clinical samples to the laboratory is required to be in adherence to all national regulations for the safe transport of biological materials. Enfer Medical provides a fully compliant logistics service, aligned with clients’ testing requirements.

Prompt transport of specimens:
To ensure prompt testing of samples and release of results within the published test turnaround times, samples should arrive to the laboratory by 18:00. Test turnaround time is measured from receipt of the sample at the laboratory until the time the authorised results are reported to users.

Acceptance/Rejection
of Samples

In rare cases specimens may not be suitable for testing on arrival to the laboratory. In that case the sample will be rejected at the receipt stage and the service user will be notified immediately and an explanation as to why the sample could not be processed will be provided. Reasons why samples cannot be processed include but are not limited to:

  • Samples received beyond the stability limits and/or not at the correct temperature indicated for each test.
  • Incorrect sample type received.
  • Leaking samples, sample not received or sample insufficient for analysis as stated below within sample requirements.
  • Non-compliant samples or request forms i.e. those missing sample date information, missing sample test request and/or missing sample site/type information.
  • Samples received without the necessary patient identifiers.
Clients will be provided with guidance on Sample Receipt Anomalies.

Our Services

Service
Health & Wellness
General health and wellness testing can include a variety of tests, depending on the needs of the individual or recommendations of
Find Out More
Service
Sexual Health
Regular STI screening facilitates early treatment and reduces the long-term consequences of infection.
Find Out More
Service
Respiratory Health
Rapid early pathogen identification has important treatment and infection control implications. See our range of tests here.
Find Out More
Service
Reproductive & Female Health
Hormonal analysis is hugely beneficial to identifying problems that can arise during the reproductive years.
Find Out More
Service
All Services
View the full suite of services at Enfer Medical here.......
Find Out More
Result Values:

Quantitative results for Magnesium are reported in numeric value in mmol/L. Please contact us for more information on the reference ranges used at Enfer Medical.

Critical results are communicated in accordance with the Communication of critical results for patients in the community- national laboratory handbook CSP041/2019

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