The main cause for elevated amylase is pancreatitis, arising in 80% of patients. Levels rise within the first few hours of the onset of pancreatitis, up to 3–4 times but can rise as high as 15 times the upper level of normal, peaking at around 48 hours. It is important to note that amylase can be normal in some cases of severe pancreatitis, especially relapsing or chronic pancreatitis. Renal failure can cause levels to rise as renal clearance is reduced.
Serum amylase is a pancreatic enzyme which is normally measured in the diagnosis of acute abdominal pain.
Higher than normal concentrations can reflect other medical conditions including pancreatic carcinoma, mumps infection, cholecystitis, mesenteric infarction, perforated duodenal ulcer, intestinal obstruction or peritonitis, hepatitis, post ERCP, trauma, DKA and acute alcohol intoxification and macroamylasaemia. Amylase may be measured in other body fluids, including urine and peritoneal fluid.
5mL venous serum or plasma
In addition to the packaging of samples, the transport/delivery of clinical samples to the laboratory is required to be in adherence to all national regulations for the safe transport of biological materials. Enfer Medical provides a fully compliant logistics service, aligned with clients’ testing requirements.
Prompt transport of specimens:
To ensure prompt testing of samples and release of results within the published test turnaround times, samples should arrive to the laboratory by 18:00. Test turnaround time is measured from receipt of the sample at the laboratory until the time the authorised results are reported to users.
In rare cases specimens may not be suitable for testing on arrival to the laboratory. In that case the sample will be rejected at the receipt stage and the service user will be notified immediately and an explanation as to why the sample could not be processed will be provided. Reasons why samples cannot be processed include but are not limited to:
- Samples received beyond the stability limits and/or not at the correct temperature indicated for each test.
- Incorrect sample type received.
- Leaking samples, sample not received or sample insufficient for analysis as stated below within sample requirements.
- Non-compliant samples or request forms i.e. those missing sample date information, missing sample test request and/or missing sample site/type information.
- Samples received without the necessary patient identifiers.
Quantitative results for Amylase are reported in numeric value in U/L. Please contact us for more information on the reference ranges used at Enfer Medical.
Critical results are communicated in accordance with the Communication of critical results for patients in the community- national laboratory handbook CSP041/2019