Albumin is the most important factor in the maintenance of plasma colloid oncotic pressure and deficiency results in oedema. Serum albumin concentrations tend to be normal in acute viral hepatitis, drug-related hepatotoxicity, and obstructive jaundice. At Enfer Medical, the bromocresol purple (BCP) method is used.
Calcium (Ca) blood tests measure how much calcium is in your blood. Your healthcare provider can use this test to help diagnose and watch many conditions.
A high level of plasma albumin – greater than 50g/l – is usually indicative of either severe dehydration or a sample that was taken from an arm at an excessively long cuffing period.
Hypoalbuminaemia, or low albumin, results in oedema and can be caused by a variety of conditions.
There are four general causes:
1) Reduced production due to chronic liver disease e.g. cirrhosis, indicating severe liver damage with subsequent reduced albumin synthesis.
2) Severe malnutrition/starvation or malabsorption states whereby total body reserves are exhausted over time.
3) Increased loss depending on the source.
– Renal, such nephrotic syndrome, results in proteinuria.
– Protein losing enteropathies which occur in the gut, Crohns and Ulcerative colitis.
– Severe acute loss due to a haemorrhage, severe burns, or chronic skin disease eg: exfoliative dermatitis.
4) Falsely reduced levels can occur in the hospitalized patient as a result of rapid or prolonged intravenous fluid therapy.
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5mL venous serum or plasma
Enfer Medical offers colorimetric BCP technology for the quantitative assay for Albumin. This test is CE-IVD certified.
For clients using the Enfer Medical Client Portal, the Enfer Medical Patient Request Form (PRF) will be generated when you have completed your “Test Request” within the portal linked below.
Please note that samples suspected of containing high risk pathogens such as Mycobacterium tuberculosis should be clearly identified on the form and packed separately from other samples.
Results available next working day.
This assay is available seven days a week.
The packaging/preparation of samples for delivery to the laboratory are required to be in adherence to all national regulations for the safe transport of biological materials. HSE guidance can be reviewed HERE.
There are specific packaging instructions and labelling requirements requiring triple packaging including:
- Primary leak-proof container – tube or vial containing the sample.
- Secondary watertight container, with absorbent material, intended to protect the primary container.
- Outer container protects the secondary container.
- Patient Request forms must be placed between the secondary container and the outer shipping container.
Further information on the packaging/preparation of samples for delivery to the laboratory is contained within the Enfer Medical Laboratory User Manual which clients are provided with.
Storage & Stability
Specimens must be tested within 6 days of collection and stored at 2-8°C.
In addition to the packaging of samples, the transport/delivery of clinical samples to the laboratory is required to be in adherence to all national regulations for the safe transport of biological materials. Enfer Medical provides a fully compliant logistics service, aligned with clients’ testing requirements.
Prompt transport of specimens:
To ensure prompt testing of samples and release of results within the published test turnaround times, samples should arrive to the laboratory by 18:00. Test turnaround time is measured from receipt of the sample at the laboratory until the time the authorised results are reported to users.
In rare cases specimens may not be suitable for testing on arrival to the laboratory. In that case the sample will be rejected at the receipt stage and the service user will be notified immediately and an explanation as to why the sample could not be processed will be provided. Reasons why samples cannot be processed include but are not limited to:
- Samples received beyond the stability limits and/or not at the correct temperature indicated for each test.
- Incorrect sample type received.
- Leaking samples, sample not received or sample insufficient for analysis as stated below within sample requirements.
- Non-compliant samples or request forms i.e. those missing sample date information, missing sample test request and/or missing sample site/type information.
- Samples received without the necessary patient identifiers.
Quantitative results for Albumin (BCP) are reported in numeric value in mmol/L. Please contact us for more information on the reference ranges used at Enfer Medical.
Following receipt at the Laboratory, results should be available on the next working day and will be reported to the referring clinician via the Enfer Medical Client Portal or in a format agreed with clients.
Established clients can login to the portal using the link above.