Progesterone has a central role in the secretory stage of the menstrual cycle, preparing the endometrium in the uterus for implantation of an embryo. Progesterone levels are typically low in the early phase of the menstrual cycle and rise after ovulation. If fertilisation occurs, the placenta takes over the production of progesterone and becomes the principal source of progesterone in the second trimester. If fertilisation does not occur, the corpus luteum regresses, progesterone levels fall and a menstrual period follows.

Measurement of serum progesterone during pregnancy is useful in determining the success of ovarian response to hormonal therapy and in the detection of ectopic or non viable pregnancies. Serum progesterone monitoring is also helpful in the management of recurrent miscarriages – insufficient levels indicating the need for prescribed supplemental progesterone support especially in early pregnancy.

Please contact us for more information on the reference ranges used at Enfer Medical.