Clinical Details

Possible causes of hyperphosphatemia include

  • Advanced renal failure – GFR <30 significantly reduces the capacity to eliminate phosphate resulting in raised levels
  • Inadequate renal excretion in the absence of chronic kidney disease also occurs in pseudohypoparathyroidism, hypoparathyroidism, and parathyroid suppression from hypercalcaemia due to vitamin A/D excess
  • Phosphate overload from large transcellular shift of phosphate into the extracellular space that exceeds the kidneys ability to process it in a timely manner : tumour lysis syndrome, rhabdomyolysis, sepsis, DKA
  • Excessive oral phosphate administration

Possible cause of hypophosphataemia  

Clinically significant acute hypophosphatemia occurs in relatively few clinical settings such as:

  • Severe respiratory alkalosis
  • After DKA treatment
  • During carbohydrate refeeding in severely malnourished patients / starvation states / alcoholism patients
  • In patients receiving TPN
  • Severe respiratory alkalosis
  • Acute alcohol use disorder
  • Severe burns
  • Long term steroid use
Case Study
At Enfer Medical, we have integrated a cutting-edge and fully automated WASPLab® (Walk Away Specimen Processor) that has significantly enhanced our testing capabilities to ensure the highest of quality when processing patient samples.
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WASPLab® at Enfer Medical
Our entire microbiology workflow has been optimized using automation and highly sophisticated robots to ensure uninterrupted incubation for rapid bacterial growth and improved turnaround times for patients.
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