High IgE 

High total IgE is common and most often associated with atopic conditions such as asthma, eczema, allergic rhinitis, or food allergy, though it is not diagnostic of allergy on its own. A raised IgE should not be used to diagnose allergy, as it may also occur in nonallergic conditions and even in ultrarare immunodysregulation disorders. Very high IgE (>1000) is particularly common in eczema.  

Low or Normal IgE 

A normal or low total IgE does not exclude allergy, because people with true clinical allergies may still have normal IgE levels. IgE must be interpreted in the context of clinical history, and that testing adds little without supporting symptoms.