High (Positive) TgAb
A positive Anti Thyroglobulin Antibody result suggests the presence of autoimmune thyroid disease, as anti thyroid antibodies may occur in conditions such as Graves’ disease or thyroiditis. High levels support an autoimmune cause when thyroid function tests are abnormal, helping to explain thyroid dysfunction.
Low or Negative TgAb
A low or absent Anti Thyroglobulin Antibody level makes autoimmune thyroid disease less likely, particularly when thyroid hormone tests are normal. In such cases, thyroid dysfunction- if present – may have a non autoimmune cause. Anti thyroid antibodies are present specifically in autoimmune conditions, so absence reduces that likelihood.
